Tim Steinfatt

joined the Beilhack lab for his PhD thesis in May 2015. He is working on cell-cell communication and signaling pathways of regulatory T cells. In his translational research project he aims to manipulate regulatory T cells in vivo in inflammation and cancer.

Tim Steinfatt studied Technical Biology at the University of Stuttgart where he received his Bachelor of Science in 2012 and his Master of Science in 2015. For his bachelor thesis he joined the automated tissue engineering group of the Fraunhofer-IPA at Stuttgart where he continued as a student assistant afterwards. As a master student he joined the research laboratory of Anna Wu at the University of California, Los Angeles (UCLA). In this distinguished laboratory he worked on the humanization of therapeutic antibodies for prostate cancer therapy.

Contact:

Tim Steinfatt, PhD student

Tel: +49-931-201 27637

Steinfatt_T@ukw.de

Publications

Medler J, Nelke J, Weisenberger D, Steinfatt T, Rothaug M, Berr S, Hünig T, Beilhack A, Wajant H. (2019). TNFRSF receptor-specific antibody fusion proteins with targeting controlled FcγR-independent agonistic activity. Cell Death Dis.10(3):224.

Chopra M, Biehl M, Steinfatt T, Brandl A, Kums J, Amich J, Vaeth M, Kuen J, Holtappels R, Podlech J, Mottok A, Kraus S, Jordán Garrote AL, Bäuerlein CA, Brede C, Ribecchini E, Fick A, Seher A, Polz J, Ottmüller K, Baker J, Nishikii H, Ritz M, Mattenheimer K, Schwinn S, Winter T, Schäfer V, Krappmann S, Einsele H, Mueller TD, Reddehase MJ, Lutz MB, Männel DN, Berberich-Siebelt F, Wajant H, Beilhack A. (2016). Exogenous TNFR2 activation protects from acute GvHD by induction of host Treg expansion. J Exp Med 213:18811900.