Katja Jarick (neé Ottmüller)

Katja Ottmüller, T cell trafficking, GVHD, Immunregulation, Immuntherapie Würzburg, Beilhack lab
joined the Beilhack Lab in 2013 for her PhD thesis to study donor T cell migration in the intestinal tract during acute GvHD. She employs flow cytometry, immunofluorescence microscopy, laser-scanning light-sheet microscopy, in vivo two-photon microscopy and bioluminescence imaging.

Additionally, she is part of the doctoral research council of the Gradudate School of Life Sciences (GSLS) Würzburg and in the organizational team of the international students’ symposium EUREKA.

Katja studied human biology for five years in Greifswald, Germany, and graduated in 2013. During her Diploma Thesis in the center for innovation competence Plasmatis of the Leibnitz Institute for Plasma Science and Technology she worked on non-thermal physical plasma-induced wound healing. More specifically, she investigated the influence of physical plasma on MAPK and p53-signaling in immune cells and keratinocytes. Thereafter, she joined the center for innovation competence HIKE in Greifswald for five months, where she studied lipid modifications and intracellular trafficking of signaling molecules involved in TCR signaling.

 

Contact:

Katja Jarick, Diplom human biologist

Tel: +49-931-201 44041

ottmueller_k@ukw.de

 

Publications:

Jarick KJ, Mokhtari Z, Scheller L, Hartweg J, Thusek S, Le DD, Ranecky M, Shaikh H, Qureischi M, Heinze KG, Beilhack A. (2018). Photoconversion of Alloreactive T Cells in Murine Peyer’s Patches During Acute Graft-Versus-Host Disease: Tracking the Homing Route of Highly Proliferative Cells In Vivo. Front. Immunol. 9:1468.

Hülsdünker J, Ottmüller KJ, Neeff HP, Koyama M, Gao Z, Thomas OS, Follo M, Al-Ahmad A, Prinz G, Duquesne S, Dierbach H, Kirschnek S, Lämmermann T, Blaser MJ, Fife BT, Blazar BR, Beilhack A, Hill GR, Häcker G, Zeiser R. (2018). Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset. Blood 131(16):1858-1869.

Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P, Kinsella S, Palikuqi B, Ginsberg M, Young LF, Kreines F, Lieberman SR, Lazrak A, Guo P, Malard F, Smith OM, Shono Y, Jenq RR, Hanash AM, Nolan DJ, Butler JM, Beilhack A, Manley NR, Rafii S, Dudakov JA, van den Brink MRM. (2018). Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration. Sci Immunol 3:19.

Chopra M, Biehl M, Steinfatt T, Brandl A, Kums J, Amich J, Vaeth M, Kuen J, Holtappels R, Podlech J, Mottok A, Kraus S, Jordán Garrote AL, Bäuerlein CA, Brede C, Ribecchini E, Fick A, Seher A, Polz J, Ottmüller K, Baker J, Nishikii H, Ritz M, Mattenheimer K, Schwinn S, Winter T, Schäfer V, Krappmann S, Einsele H, Mueller TD, Reddehase MJ, Lutz MB, Männel DN, Berberich-Siebelt F, Wajant H, Beilhack A. (2016). Exogenous TNFR2 activation protects from acute GvHD by induction of host Treg expansion. J Exp Med 213:18811900.

Bundscherer L, Wende K, Ottmüller K, Barton A, Schmidt A, Bekeschus S, Hasse S, Weltmann KD, Masur K, Lindequist U. (2013). Impact of non-thermal plasma treatment on MAPK signaling pathways of human immune cell lines. Immunobiology 218(10):1248-1255.

Schmidt A, Wende K, Bekeschus S, Bundscherer L, Barton A, Ottmüller K, Weltmann KD, Masur K. (2013). Non-thermal plasma treatment is associated with changes in transcriptome of human epithelial skin cells. Free Radic Res. 47(8):577-592.